Cilastatin

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0082009-34-5

Chemical Formula

C16-H26-N2-O5-S

Molecular Weight

358

Therapeutic Category

Enzyme inhibitor

Chemical Name

2-Heptenoic acid, 7-[(2-amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-, [R-[R*,S*-(Z)]]-

Foreign Names

• Cilastatinum (Latin)
• Cilastatin (German)
• Cilastatine (French)
• Cilastatina (Spanish)

Generic Names

• Cilastatin (OS: BAN)
• Cilastatin Sodium (OS: JAN, USAN, BANM)
• MK 791 (IS: Merck)
• Cilastatin Sodium (PH: BP 2010, USP 32, Ph. Eur. 6)
• Cilastatine sodique (PH: Ph. Eur. 6)
• Cilastatin-Natrium (PH: Ph. Eur. 6)
• Cilastatinum natricum (PH: Ph. Eur. 6)

Brand Names

• I-NEM (Cilastatin and Imipenem)
  Glenmark, India



• Pelastin (Cilastatin and Imipenem)
  Sanbe, Indonesia



• Synergic (Cilastatin and Imipenem)
  Unimed, Tunisia



• Tienam (Cilastatin and Imipenem)
  Banyu Seiyaku, Japan; Merck Sharp & Dohme, Tunisia; Merck Sharp & Dohme, Turkey



• Tiepenem (Cilastatin and Imipenem)
  Shiono Kemikaru, Japan



• Bacqure
  Ranbaxy, China



• Bacqure (Cilastatin and Imipenem)
  Ranbaxy, Peru



• Conet (Cilastatin and Imipenem)
  Merck Sharp & Dohme, Slovenia



• Imipem (Cilastatin and Imipenem)
  Neopharmed, Italy



• Imipénem Cilastatine Mylan (Cilastatin and Imipenem)
  Mylan, France



• Imipénem Cilastatine Ranbaxy (Cilastatin and Imipenem)
  Ranbaxy, France



• Imipenem und Cilastatin HSP (Cilastatin and Imipenem)
  Hospira, Germany



• Imipenem/Cilastatin Fresenius Kabi (Cilastatin and Imipenem)
  Fresenius, Sweden



• Imipenem/Cilastatin Hexal (Cilastatin and Imipenem)
  Hexal, Germany



• Imipenem/Cilastatin Teva (Cilastatin and Imipenem)
  Teva Pharma, Switzerland



• Imipenem-Cilastatin Hospira (Cilastatin and Imipenem)
  Hospira, Switzerland



• Imipenem-Cilastatin Labatec (Cilastatin and Imipenem)
  Labatec, Switzerland



• Imistan (Cilastatin and Imipenem)
  Nichi-Iko PharmaceuticalJMA, Japan



• Indast (Cilastatin and Imipenem)
  Taiyo Pharmaceutical, Japan



• Inem (Cilastatin and Imipenem monohydrate)
  Labinco, Colombia



• Primaxin (Cilastatin and Imipenem)
  Merck, United States; Merck Frosst, Canada; Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, United Kingdom; Merck Sharp & Dohme, Malta; Merck Sharp & Dohme, New Zealand



• Tenacid (Cilastatin and Imipenem monohydrate)
  Sigma Tau, Italy



• Tienam (Cilastatin and Imipenem)
  Merck, Peru; Merck Sharp & Dhome, Oman; Merck Sharp & Dohme, Bosnia & Herzegowina; Merck Sharp & Dohme, Belgium; Merck Sharp & Dohme, Bulgaria; Merck Sharp & Dohme, Chile; Merck Sharp & Dohme, China; Merck Sharp & Dohme, Colombia; Merck Sharp & Dohme, Costa Rica; Merck Sharp & Dohme, Czech Republic; Merck Sharp & Dohme, Algeria; Merck Sharp & Dohme, Ecuador; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Spain; Merck Sharp & Dohme, France; Merck Sharp & Dohme, Guatemala; Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Honduras; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Israel; Merck Sharp & Dohme, Iceland; Merck Sharp & Dohme, Italy; Merck Sharp & Dohme, Sri Lanka; Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Luxembourg; Merck Sharp & Dohme, Latvia; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, Nicaragua; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, Panama; Merck Sharp & Dohme, Philippines; Merck Sharp & Dohme, Poland; Merck Sharp & Dohme, Portugal; Merck Sharp & Dohme, Romania; Merck Sharp & Dohme, Serbia; Merck Sharp & Dohme, Russian Federation; Merck Sharp & Dohme, Sweden; Merck Sharp & Dohme, Singapore; Merck Sharp & Dohme, Slovakia; Merck Sharp & Dohme, El Salvador; Merck Sharp & Dohme, Thailand; Merck Sharp & Dohme, Taiwan; Merck Sharp & Dohme, South Africa; MSD, Switzerland; MSD, Finland; MSD, Indonesia; MSD, Norway



• Tilam (Cilastatin and Imipenem)
  Merck, Taiwan



• Zienam (Cilastatin and Imipenem)
  Merck Sharp & Dohme, Austria; Merck Sharp & Dohme, Germany; Merck Sharp & Dohme, Venezuela

International Drug Name Search

Glossary

BAN	British Approved Name
BANM	British Approved Name (Modified)
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.